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KMID : 1123920090230020438
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Korean Journal of Oriental Physiology and Pathology
2009 Volume.23 No. 2 p.438 ~ p.442
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Effect of Artemisiae Argi Folium Fermented with Lactobacillus Pentosus on Hydrogen Peroxide Production of Macrophage Treated with Toxicants
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Park Wan-Su
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Abstract
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The purpose of this study is to investigate the effect of water extract from Artemisiae Argi Folium Fermented with Lactobacillus pentosus (AFL) on hydrogen peroxide production within mouse macrophage Raw 264.7 Cells treated with gallic acid, EtOH, Nicotine, Acetaminophen, and Acetaldehyde. AFL (0400 ug/mL) was treated with gallic acid, EtOH, Nicotine, Acetaminophen, and Acetaldehyde. And the intracellular productions of hydrogen peroxide were measured by dihydrorhodamine 123 (DHR) assay. AFL showed the restoration of the intracellular productions of hydrogen peroxide which were reduced by gallic acid, EtOH, Nicotine, Acetaminophen in Raw 264.7 Cells. AFL could be supposed to have the immunological activity related with macrophage’s oxidative burst.
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KEYWORD
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macrophage, lactobacillus pentosus, artemisiae argi folium, fermentation, hydrogen peroxide
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